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Compound category: Benzenoids
(total 233 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Sibofimloc Depiction based on curated SMILES HO HO HO HO O OH OH HO HO O N CH 3 O Escherichia Adherence Phase II trial Chevalier G, et al. 2021. Microbiome; Reinisch W, et al. 2022. J Gastroenterol Hepatol
Fluorothiazinon Depiction based on curated SMILES OH O S F F H 3 C NH O N N O Acinetobacter
Chlamydia
Klebsiella
Pseudomonas
Salmonella		 Biofilm
TTSS (Type III secretion system)
Biofilm
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vitro)
Preclinical (in vivo)
Phase II trial		 Bondareva NE, et al. 2022. J Antibiot (Tokyo)
Zigangirova NA, et al. 2012. Acta Naturae; Koroleva EA, et al. 2015. Biomed Res Int; Zigangirova NA, et al. 2016. J Med Microbiol
Tsarenko SV, et al. 2023. J Antibiot (Tokyo)
Sheremet AB, et al. 2018. Biomed Res Int
Nesterenko LN, et al. 2016. J Antibiot (Tokyo); Zigangirova NA, et al. 2021. J Antibiot (Tokyo)
ML364 Depiction based on curated SMILES S F F F S O O HN H 3 C O N H N Klebsiella
Pseudomonas
Staphylococcus		 Biofilm; Biofilm
Pyocyanin
Biofilm		 Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vivo)		 Zhang Y, et al. 2022. Front Microbiol
2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide Depiction based on curated SMILES NH O NH O _ O O + N N S Pseudomonas Biofilm Preclinical (in vivo) Starkey M, et al. 2014. PLoS Pathog
N-(4-cyanophenyl)-2-fluoro-N'-(4-phenoxyphenyl)propanediamide Depiction based on curated SMILES O N N H O F O HN Pseudomonas Biofilm Preclinical (in vivo) Singh VK, et al. 2022. Nat Commun
1-phenyl-3-[4-(phenylsulfamoyl)phenyl]thiourea Depiction based on curated SMILES NH S N H O HN O S Escherichia
Salmonella		 Regulation
QseBC		 Preclinical (in vivo)
Preclinical (in vivo)		 Rasko DA, et al. 2008. Science
({1-[2-(2-fluorophenyl)ethyl]-4-piperidinyl}methyl)methyl(3-thienylmethyl)amine Depiction based on curated SMILES S F CH 3 N N Salmonella Biofilm Preclinical (in vivo) Woolard KJ, et al. 2022. Eur J Med Chem
Dephostatin Depiction based on curated SMILES CH 3 N OH HO N O Salmonella PmrAB; SsrAB Preclinical (in vivo) Tsai CN, et al. 2020. Cell Chem Biol
Compound 7b
(internal name in literature)		 Depiction based on curated SMILES N Cl Cl CH 3 S N Salmonella Biofilm Preclinical (in vivo) Woolard KJ, et al. 2022. Eur J Med Chem
Compound 7d
(internal name in literature)		 Depiction based on curated SMILES N Br Br CH 3 S N Salmonella Biofilm Preclinical (in vivo) Woolard KJ, et al. 2022. Eur J Med Chem
   


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