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2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide

Drug details:
Molecular formula: C21H16N4O4S

Classification: Diphenylethers; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES NH O NH O _ O O + N N S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vivo)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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