Drug details:
Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;

Curated SMILES: CC1=CC=C(CCNC2=NC=C(C(=O)NC3=CC=C(C4=CN=C(N)N4)C=C3)C=N2)C=C1

Evidence for compound's anti-virulence activity:

Clostridium
Related VFcategory: Exotoxin; Regulation
Target: Not determined
Drug effect: Targets two-component systems to interfere with signaling pathways thereby inhibiting virulence responses such as antibiotic resistance, toxin secretion and biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Thanissery R, et al., 2018. A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile. Front Microbiol 9:1206.