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4-[(3-ethoxy-2-hydroxyphenyl)methyl]-N-(4-fluorophenyl)-5-oxo-1,3,4-thiadiazine-2-carboxamide

Drug details:
Molecular formula: C19H18FN3O4S

Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES O S F H 3 C NH O N N OH O

Evidence for compound's anti-virulence activity:

Chlamydia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits T3SS activity and disrupts progression of the chlaymdial development cycle.
Max phase: Preclinical (in vitro)
Publication:
Zigangirova NA, et al., 2012. Development of Chlamydial Type III Secretion System Inhibitors for Suppression of Acute and Chronic Forms of Chlamydial Infection. Acta Naturae 4(2):87-97.








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