Drug details:
Molecular formula: C₁₇H₁₃N₃O₂

Standard name: N-(2-carbamoylphenyl)quinoline-3-carboxamide

Curated SMILES: C1=CC=C2C(=C1)C=C(C=N2)C(=O)NC3=CC=CC=C3C(=O)N

Evidence for compound's anti-virulence activity:

Streptococcus
Related VF: Streptococcal glucosyltransferases
Target: GtfC
Drug effect: Inhibits biofilms formation by inhibiting Glucosyl transferases Gtfs activity.
Max phase: Preclinical (in vivo)
Publication:
Nijampatnam B, et al., 2021. Discovery of Potent Inhibitors of Streptococcus mutans Biofilm with Antivirulence Activity. ACS Med Chem Lett 12(1):48-55.