Drug details:
Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;

Curated SMILES: NC(=O)SCC(=O)N(CC1=CC=CC(Cl)=C1)C1=CC(Cl)=C(Cl)C=C1

Evidence for compound's anti-virulence activity:

Bacillus
Related VF: Collagenase
Target: ColQ1
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to reduce cytotoxicity to host cells.
Max phase: Preclinical (in vivo)
Publication:
Alhayek A, et al., 2022. Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections. Adv Ther (Weinh) 5(3):2100222.