Drug details:
Molecular formula: C₁₇H₂₃NO₄

Standard name: 3-[(4-methoxyphenyl)carbamoyl]-1,2,2-trimethylcyclopentane-1-carboxylic acid

Synonyms:

3-[(4-methoxyphenyl)carbamoyl]-1,2,2-trimethylcyclopentane-1-carboxylic acid 3-((4-Methoxyphenyl)carbamoyl)-1,2,2-trimethylcyclopentane-1-carboxylic acid 3-{[(4-methoxyphenyl)amino]carbonyl}-1,2,2-trimethylcyclopentanecarboxylic acid 3-(4-Methoxyphenylcarbamoyl)-1,2,2-trimethylcyclopentanecarboxylic acid 3-[(4-methoxyphenyl)carbamoyl]-1,2,2-trimethylcyclopentanecarboxylic acid 3-[(4-Methoxyanilino)carbonyl]-1,2,2-trimethylcyclopentanecarboxylic acid #

Curated SMILES: COC1=CC=C(NC(=O)C2CCC(C)(C(=O)O)C2(C)C)C=C1

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.