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N-phenyl-2-{[4-(thiophen-2-yl)pyrimidin-2-yl]sulfanyl}acetamide

Drug details:
Molecular formula: C16H13N3OS2

Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Synonym:  N-phenyl-2-{[4-(2-thienyl)-2-pyrimidinyl]sulfanyl}acetamide

Chemical structure:
Depiction based on curated SMILES NH N S O N S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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