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Compound category: Carboxylic acids and derivatives
(total 8 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Zosurabalpin Depiction based on curated SMILES NH 2 NH 2 N O OH N H N O N H S CH 3 N H O N H O Acinetobacter LPS Phase I trial Pahil KS, et al. 2024. Nature; Que W, et al. 2024. Trends Mol Med
N-(2-{(2Z)-2-[1-(1,3-benzodioxol-5-ylmethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)pyridine-3-carboxamide Depiction based on curated SMILES O N O N H O O N N H N O Acinetobacter Regulation Preclinical (in vivo) Trebosc V, et al. 2022. Virulence
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-1-benzyl-4,5-dibromopyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES Br ClH NH 2 HN N HN O Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-(2-phenylethyl)pyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES Br ClH NH 2 N H N HN O Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-cyclopentylpyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES ClH NH 2 N H N N H O Br Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-ethylpyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES NH ClH H 2 N NH N H 3 C O Br Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
5beta,6alpha-Bis[4-[(4,5-dibromo-1H-pyrrole-2-yl)carbonylaminomethyl]-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N H N NH O N Br Br N H N N N H N H N NH 2 N H O Br Br HN Acinetobacter
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
ZINC Lactate Depiction based on curated SMILES CH 3 O _ O HO CH 3 O _ O HO 2+ Zn Acinetobacter PNAG Preclinical (in vitro) Peng Q, et al. 2020. Sci Rep
   
   
   
   
   


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