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Compound category: Naphthalenes
(total 2 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Sepantronium bromide Depiction based on curated SMILES _ Br N N O CH 3 O H 3 C O N + N Escherichia
Salmonella		 TTSS secreted effectors
TTSS-2 secreted effectors		 Phase II trial
Preclinical (in vitro)		 El Qaidi S, et al. 2018. Front Cell Infect Microbiol; Zhu C, et al. 2021. Pathogens
4-chloro-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Depiction based on curated SMILES Cl O OH N N H Chlamydia
Salmonella
Shigella		 TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Muschiol S, et al. 2006. Proc Natl Acad Sci U S A
Negrea A, et al. 2007. Antimicrob Agents Chemother
Veenendaal AK, et al. 2009. J Bacteriol
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   


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