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Chlorzoxazone

Drug details:
Molecular formula: C7H4ClNO2

Classification: Benzoxazolones; Benzoxazoles; Organoheterocyclic compounds; Organic compounds;
Synonyms:  Paraflex
Chlorzoxazon
5-Chloro-2-benzoxazolone
Chloroxazone
5-Chloro-2-benzoxazolinone
2(3H)-Benzoxazolone, 5-chloro-
5-Chloro-2(3H)-benzoxazolone
Biomioran
Escoflex
......

Curated SMILES: O=C1NC2=CC(Cl)=CC=C2O1
Chemical structure:
Depiction based on curated SMILES O N H Cl O

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Invasion
Target: Not determined
Drug effect: Inhibits bacterial invasion and intracellular replication.
Max phase: Preclinical (in vitro)
Publication:
Ridge Y, et al., 2018. High-throughput screening of a collection of known pharmacologically active small compounds for inhibitors of Salmonella invasion and intracellular replication. J Appl Microbiol 125(3):724-730.








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