Drug details:
Molecular formula: C₁₃H₁₂ClFN₂O₃

Standard name: 1-tert-butyl-7-chloro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Curated SMILES: CC(C)(C)N1C=C(C(=O)O)C(=O)C2=CC(F)=C(Cl)N=C21

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits the ompA expression and biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Na SH, et al., 2021. Screening of small molecules attenuating biofilm formation of Acinetobacter baumannii by inhibition of ompA promoter activity. J Microbiol 59(9):871-878.