Drug details:
Molecular formula: C₁₃H₁₁FN₂O₄

Standard name: 5-fluoro-1-[3-(hydroxymethyl)-1,3-dihydro-2-benzofuran-1-yl]pyrimidine-2,4-dione

Curated SMILES: O=C1NC(=O)N(C2OC(CO)C3=C2C=CC=C3)C=C1F

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits the ompA expression and biofilm formation.
Max phase: Preclinical (in vitro)
Publications:
Na SH, et al., 2021. Screening of small molecules attenuating biofilm formation of Acinetobacter baumannii by inhibition of ompA promoter activity. J Microbiol 59(9):871-878.
Na SH, et al., 2021. Therapeutic Effects of Inhibitor of ompA Expression against Carbapenem-Resistant Acinetobacter baumannii Strains. Int J Mol Sci 22(22):12257.