Drug details:
Molecular formula: C₂₈H₃₂N₂O₄

Standard name: 3,4,5-trimethoxy-N-(5,5,6,6-tetramethylbenzo[b][1]benzazepin-11-yl)benzamide

Curated SMILES: CC1(C2=CC=CC=C2N(C3=CC=CC=C3C1(C)C)NC(=O)C4=CC(=C(C(=C4)OC)OC)OC)C

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: DGC
Drug effect: Inhibits of diguanylate cyclase (DGC) enzymes that synthesize c-di-GMP that is essential for biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Sambanthamoorthy K, et al., 2015. Modulating Acinetobacter baumannii biofilm development with molecules containing 3,4,5-trimethoxy-N,N',N'-trimethylbenzohydrazide moiety. Bioorg Med Chem Lett 25(10):2238-42.