Drug details:
Molecular formula: C₁₄H₁₄O₂S

Standard name: 2-(2-hydroxy-5-methylphenyl)sulfanyl-4-methylphenol

Synonyms:

2,2'-Thiodi-p-cresol 2,2-Thiobis(4-methylphenol) Bis(2-hydroxy-5-methylphenyl)sulfide

Curated SMILES: CC1=CC=C(O)C(SC2=CC(C)=CC=C2O)=C1

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits T3SS.
Max phase: Preclinical (in vitro)
Publication:
Jessen DL, et al., 2014. A type III secretion system inhibitor targets YopD while revealing differential regulation of secretion in calcium-blind mutants of Yersinia pestis. Antimicrob Agents Chemother 58(2):839-50.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: YopD
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Jessen DL, et al., 2014. A type III secretion system inhibitor targets YopD while revealing differential regulation of secretion in calcium-blind mutants of Yersinia pestis. Antimicrob Agents Chemother 58(2):839-50.