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N-(3,4-dichlorophenyl)-2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetamide

Drug details:
Molecular formula: C16H13Cl2N3O2S

Classification: Benzimidazoles; Organoheterocyclic compounds; Organic compounds;
Synonym:  N-(3,4-dichlorophenyl)-2-[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetamide

Chemical structure:
Depiction based on curated SMILES N H N Cl Cl CH 3 O S N H O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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