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2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide

Drug details:
Molecular formula: C15H12N2O2S

Classification: Benzoxazoles; Organoheterocyclic compounds; Organic compounds;
Synonyms:  Acetamide, 2-(2-benzoxazolylthio)-N-phenyl-
2-(Benzo[d]oxazol-2-ylthio)-N-phenylacetamide
2-(1,3-benzoxazol-2-ylthio)-N-phenylacetamide

Chemical structure:
Depiction based on curated SMILES NH O O N S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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