Drug details:
Molecular formula: C₂₅H₂₅N₃O₃

Standard name: 3'-[(3Z)-2-oxo-3-(1,3,3-trimethylindol-2-ylidene)propyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione

Curated SMILES: CN1C2=CC=CC=C2C(C)(C)/C1=C/C(=O)CN1C(=O)NC2(CCC3=C2C=CC=C3)C1=O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.