Drug details:
Molecular formula: C₂₆H₂₄N₄OS

Standard name: N-benzyl-2-[[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanyl]acetamide

Curated SMILES: CC1=CC=C(C2=NN=C(SCC(=O)NCC3=CC=CC=C3)N=C2C2=CC=C(C)C=C2)C=C1

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.