Drug details:
Molecular formula: C₁₇H₂₂N₄O₄S₂

Standard name: N,1-dimethyl-5-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonylamino)carbamoyl]pyrrole-3-sulfonamide

Curated SMILES: CNS(=O)(=O)C1=CN(C)C(C(=O)NNC(=O)C2=CC3=C(CCCCC3)S2)=C1

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: DGC
Drug effect: Inhibits of diguanylate cyclase (DGC) enzymes that synthesize c-di-GMP that is essential for biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Sambanthamoorthy K, et al., 2014. Identification of small molecules inhibiting diguanylate cyclases to control bacterial biofilm development. Biofouling 30(1):17-28.