Drug details:
Molecular formula: C₁₅H₁₂O₇

Standard name: 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one

Synonyms:

2,3-Dihydrorobinetin Robinetin, dihydro- Hydrorobinetin 3,3',4',5',7-Pentahydroxyflavanone 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one EINECS 224-486-0 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)- (2R-trans)-2,3-Dihydro-3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-benzopyrone ......

Curated SMILES: O=C1C2=CC=C(O)C=C2OC(C2=CC(O)=C(O)C(O)=C2)C1O

Evidence for compound's anti-virulence activity:

Clostridium
Related VF: Collagenase
Target: ColA
Drug effect: Inhibits collagenase activity to block the colonization and infiltration of the host by the bacteria.
Max phase: Preclinical (in vitro)
Publication:
Nitulescu G, et al., 2022. Discovery of New Microbial Collagenase Inhibitors. Life (Basel) 12(12):2114.