Drug details:
Molecular formula: C₂H₃KO₂

Standard name: potassium;acetate

Synonyms:

Diuretic salt ACETIC ACID, POTASSIUM SALT Potassium ethanoate potassium acetate KOAc Acetic acid potassium salt Octan draselny Kali aceticum ......

Curated SMILES: CC(=O)[O-].[K+]

Evidence for compound's anti-virulence activity:

Clostridium
Related VF: TcdA (Toxin A)
Target: ToxA
Drug effect: Inhibits toxin A-induced deacetylation of tubulin and recovers toxin A-induced microtubule disassembly.
Max phase: Preclinical (in vitro)
Publication:
Lu LF, et al., 2016. Potassium Acetate Blocks Clostridium difficile Toxin A-Induced Microtubule Disassembly by Directly Inhibiting Histone Deacetylase 6, Thereby Ameliorating Inflammatory Responses in the Gut. J Microbiol Biotechnol 26(4):693-9.