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2-[(2E)-2-[(3,5-dibromo-2-hydroxyphenyl)methylidene]hydrazinyl]-2-sulfanylidene-N-[3-(trifluoromethyl)phenyl]acetamide

Drug details:
Molecular formula: C16H10Br2F3N3O2S

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES OH Br Br N N H S O F F F NH

Evidence for compound's anti-virulence activity:

Chlamydia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits T3SS activity and disrupts progression of the chlaymdial development cycle.
Max phase: Preclinical (in vitro)
Publication:
Zigangirova NA, et al., 2012. Development of Chlamydial Type III Secretion System Inhibitors for Suppression of Acute and Chronic Forms of Chlamydial Infection. Acta Naturae 4(2):87-97.








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