Drug details:
Molecular formula: C₂₁H₁₈FN₃OS

Standard name: 3-(4-fluorophenyl)-2-methyl-5-[(4-methylphenyl)sulfanylmethyl]-1H-pyrazolo[1,5-a]pyrimidin-7-one

Synonym:

3-(4-fluorophenyl)-2-methyl-5-{[(4-methylphenyl)thio]methyl}pyrazolo[1,5-a]pyrimidin-7(4H)-one

Curated SMILES: CC1=CC=C(C=C1)SCC2=CC(=O)N3C(=N2)C(=C(N3)C)C4=CC=C(C=C4)F

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.