Drug details:
Molecular formula: C₁₉H₁₇ClN₄O

Standard name: 1-(5-chloro-2-methylphenyl)-5-imino-4-(6-methyl-1H-benzimidazol-2-yl)-2H-pyrrol-3-ol

Curated SMILES: CC1=CC2=C(C=C1)N=C(N2)C3=C(CN(C3=N)C4=C(C=CC(=C4)Cl)C)O

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.