Drug details:
Molecular formula: C₂₈H₁₂N₄O₄S

Standard name: 4-[8-(3,4-dicyanophenoxy)-5,5-dioxodibenzothiophen-2-yl]oxybenzene-1,2-dicarbonitrile

Curated SMILES: N#CC1=C(C#N)C=C(OC2=CC=C3C(=C2)C2=C(C=CC(OC4=CC(C#N)=C(C#N)C=C4)=C2)S3(=O)=O)C=C1

Evidence for compound's anti-virulence activity:

Vibrio
Related VF: VAS T6SS
Target: VipA/MglA; VipB/MglB
Drug effect: Blocks the binding of VipA-VipB interaction to block T6S.
Max phase: Preclinical (in vitro)
Publication:
Sun K, et al., 2014. Screening for inhibition of Vibrio cholerae VipA-VipB interaction identifies small-molecule compounds active against type VI secretion. Antimicrob Agents Chemother 58(7):4123-30.