Drug details:
Molecular formula: C₂₈H₁₇Cl₂IN₂O₄

Standard name: [4-[[2-(3-iodophenyl)-1,3-benzoxazol-5-yl]iminomethyl]-2-methoxyphenyl] 2,4-dichlorobenzoate

Synonyms:

[4-[[2-(3-iodophenyl)-1,3-benzoxazol-5-yl]iminomethyl]-2-methoxyphenyl] 2,4-dichlorobenzoate 2,4-Dichloro-benzoic acid 4-{[2-(3-iodo-phenyl)-benzooxazol-5-ylimino]-methyl}-2

Curated SMILES: COC1=C(C=CC(=C1)C=NC2=CC3=C(C=C2)OC(=N3)C4=CC(=CC=C4)I)OC(=O)C5=C(C=C(C=C5)Cl)Cl

Evidence for compound's anti-virulence activity:

Vibrio
Related VF: VAS T6SS
Target: VipA/MglA; VipB/MglB
Drug effect: Blocks the binding of VipA-VipB interaction to block T6S.
Max phase: Preclinical (in vitro)
Publication:
Sun K, et al., 2014. Screening for inhibition of Vibrio cholerae VipA-VipB interaction identifies small-molecule compounds active against type VI secretion. Antimicrob Agents Chemother 58(7):4123-30.