Drug details:
Molecular formula: C₇H₉N₃OS

Standard name: 6-methyl-3-prop-2-enylsulfanyl-4H-1,2,4-triazin-5-one

Synonyms:

1,2,4-Triazin-5(2H)-one, 6-methyl-3-(2-propenylthio)- As-triazin-5-ol, 3-(allylthio)-6-methyl- 3-(allylthio)-6-methyl-1,2,4-triazin-5(4H)-one 1,2,4-Triazin-5(2H)-one, 6-methyl-3-(2-propen-1-ylthio)- 3-(Allylthio)-6-methyl-1,2,4-triazin-5(2H)-one 6-methyl-3-(prop-2-en-1-ylsulfanyl)-4,5-dihydro-1,2,4-triazin-5-one 6-methyl-3-prop-2-enylsulfanyl-2H-1,2,4-triazin-5-one 3-ALLYLSULFANYL-6-METHYL-4H-[1,2,4]TRIAZIN-5-ONE 6-methyl-3-(prop-2-en-1-ylsulfanyl)-1,2,4-triazin-5-ol ......

Curated SMILES: C=CCSC1=NN=C(C)C(O)=N1

Evidence for compound's anti-virulence activity:

Klebsiella
Related VF: Capsule; LPS
Target: Not determined
Drug effect: Prevents biosynthesis of the Klebsiella capsule and lipopolysaccharides.
Max phase: Preclinical (in vivo)
Publication:
Benghezal M, et al., 2007. Inhibitors of bacterial virulence identified in a surrogate host model. Cell Microbiol 9(5):1336-42.

Pseudomonas
Related VF: LPS
Target: Not determined
Drug effect: Prevents biosynthesis of the capsule and lipopolysaccharides.
Max phase: Preclinical (in vivo)
Publication:
Benghezal M, et al., 2007. Inhibitors of bacterial virulence identified in a surrogate host model. Cell Microbiol 9(5):1336-42.