Drug details:
Molecular formula: C₁₆H₁₂O₅

Standard name: 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one

Synonyms:

4',7-Dihydroxy-6-methoxyisoflavone 4-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy- 7,4'-Dihydroxy-6-methoxyisoflavone 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 7,4 inverted exclamation mark -Dihydroxy-6 methoxyisoflavone Glycetein 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one ......

Curated SMILES: COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O

Evidence for compound's anti-virulence activity:

Klebsiella
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits formation of curli.
Max phase: Preclinical (in vitro)
Publication:
Adeosun IJ, et al., 2022. Anti-Biofilm and Associated Anti-Virulence Activities of Selected Phytochemical Compounds against Klebsiella pneumoniae. Plants (Basel) 11(11):1429.