Drug details:
Molecular formula: C₁₂H₂₂O₂

Standard name: 6-heptyloxan-2-one

Synonyms:

6-Heptyltetrahydro-2H-pyran-2-one delta-Dodecanolactone Dodecan-5-olide 6-heptyloxan-2-one 2H-Pyran-2-one, 6-heptyltetrahydro- 5-Dodecalactone Dodecanolide-1,5 5-Hydroxydodecanoic acid lactone xi-5-Dodecanolide ......

Curated SMILES: CCCCCCCC1CCCC(=O)O1

Evidence for compound's anti-virulence activity:

Streptococcus
Related VFcategory: Biofilm; Regulation
Target: Not determined
Drug effect: Inhibits biofilm formation and virulence of Streptococcus pyogenes by suppressing core regulons of virulence.
Max phase: Preclinical (in vivo)
Publication:
Valliammai A, et al., 2020. 5-Dodecanolide inhibits biofilm formation and virulence of Streptococcus pyogenes by suppressing core regulons of virulence. Life Sci 262:118554.