Drug details:
Molecular formula: C₁₆H₁₁N₃O₄S

Standard name: N-(2-carbamoylphenyl)-5-nitro-1-benzothiophene-2-carboxamide

Curated SMILES: C1=CC=C(C(=C1)C(=O)N)NC(=O)C2=CC3=C(S2)C=CC(=C3)[N+](=O)[O-]

Evidence for compound's anti-virulence activity:

Streptococcus
Related VF: Streptococcal glucosyltransferases
Target: GtfC
Drug effect: Inhibits biofilms formation by inhibiting Glucosyl transferases Gtfs activity.
Max phase: Preclinical (in vivo)
Publication:
Nijampatnam B, et al., 2021. Discovery of Potent Inhibitors of Streptococcus mutans Biofilm with Antivirulence Activity. ACS Med Chem Lett 12(1):48-55.