Drug details:
Molecular formula: C₂₄H₂₇N₃O₆S

Standard name: N-(1,3-benzodioxol-5-ylmethyl)-1-[(2-oxo-1,3,4,5-tetrahydro-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide

Curated SMILES: O=C1CCCC2=CC(S(=O)(=O)N3CCC(C(=O)NCC4=CC=C5OCOC5=C4)CC3)=CC=C2N1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: TTSS (Type III secretion system)
Target: Spa47; IpaC
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vivo)
Publication:
Case HB, et al., 2020. Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion. Biochemistry 59(28):2667-2678.