Drug details:
Classification: N-arylamides; Organonitrogen compounds; Organic nitrogen compounds; Organic compounds;

Curated SMILES: CC1=CC=C(N2N=C(C3=NOC(CCCC(=O)NC4=CC=C(Cl)C=N4)=N3)C(=O)N(C)C2=O)C=C1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: TTSS (Type III secretion system)
Target: Spa47; IpaC
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vivo)
Publication:
Case HB, et al., 2020. Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion. Biochemistry 59(28):2667-2678.