Drug details:
Molecular formula: C₁₅H₁₆N₄S₂

Standard name: 3,5-bis(pyridin-3-ylmethyl)-1,3,5-thiadiazinane-2-thione

Synonyms:

Cyto10B2 3,5-bis(pyridin-3-ylmethyl)-1,3,5-thiadiazinane-2-thione CCG-50009 3,5-bis(3-pyridylmethyl)-1,3,5-thiadiazinane-2-thione 3,5-bis(3-pyridinylmethyl)-1,3,5-thiadiazinane-2-thione 3,5-Bis(3-pyridylmethyl)-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazine-2-thione

Curated SMILES: C1=CC=NC=C1CN1CSC(=S)N(CC2=CN=CC=C2)C1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publication:
Hurt JK, et al., 2010. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. J Biomol Screen 15(4):379-87.