Drug details:
Molecular formula: C₁₁H₁₄F₃NO₃S

Standard name: 4-[[5-methyl-2-(trifluoromethyl)furan-3-yl]methyl]-1,4-thiazinane 1,1-dioxide

Curated SMILES: C1N(CCS(=O)(=O)C1)CC1=C(OC(C)=C1)C(F)(F)F

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publication:
Hurt JK, et al., 2010. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. J Biomol Screen 15(4):379-87.