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CCG-21496

Drug details:
Molecular formula: C22H19N3O

Classification: 8-hydroxyquinolines; Quinolines and derivatives; Organoheterocyclic compounds; Organic compounds;
Synonym:  7-[(4-methylphenyl)(pyridin-2-ylamino)methyl]quinolin-8-ol

Chemical structure:
Depiction based on curated SMILES N N H OH N CH 3

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publication:
Hurt JK, et al., 2010. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. J Biomol Screen 15(4):379-87.








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