Drug details:
Molecular formula: C₁₄H₁₁ClN₂O

Standard name: 6-chloro-2-(phenoxymethyl)-1H-benzimidazole

Synonyms:

6-chloro-2-(phenoxymethyl)-1H-benzimidazole 5-chloro-2-phenoxymethylbenzimidazole 5-chloro-2-(phenoxymethyl)-1H-benzimidazole

Curated SMILES: C1=C2N=C(NC2=CC(Cl)=C1)COC1=CC=CC=C1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publications:
Emanuele AA, et al., 2014. Potential novel antibiotics from HTS targeting the virulence-regulating transcription factor, VirF, from Shigella flexneri. J Antibiot (Tokyo) 67(5):379-86.
Emanuele AA, et al., 2015. Mechanism of Action and Initial, In Vitro SAR of an Inhibitor of the Shigella flexneri Virulence Regulator VirF. PLoS One 10(9):e0137410.