Drug details:
Molecular formula: C₂₀H₁₉N₃O₂

Standard name: N,N-dimethyl-2-[(2-phenyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)oxy]ethanamine

Synonyms:

dimethyl-[2-(2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)oxyethyl]amine N,N-dimethyl-2-[(2-phenyl-4-benzofuro[3,2-d]pyrimidinyl)oxy]ethanamine N,N-dimethyl-2-[(2-phenyl[1]benzofuro[3,2-d]pyrimidin-4-yl)oxy]ethanamine

Curated SMILES: CN(C)CCOC1=NC(=NC2C3C=CC=CC=3OC1=2)C1=CC=CC=C1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publications:
Emanuele AA, et al., 2014. Potential novel antibiotics from HTS targeting the virulence-regulating transcription factor, VirF, from Shigella flexneri. J Antibiot (Tokyo) 67(5):379-86.
Emanuele AA, et al., 2015. Mechanism of Action and Initial, In Vitro SAR of an Inhibitor of the Shigella flexneri Virulence Regulator VirF. PLoS One 10(9):e0137410.