Drug details:
Molecular formula: C₂₈H₂₁N₃O₆

Standard name: [1-(1H-indol-3-yl)-1-oxopropan-2-yl] 2-(4-acetamidophenyl)-1,3-dioxoisoindole-5-carboxylate

Curated SMILES: CC(=O)NC1=CC=C(N2C(=O)C3=C(C=C(C(=O)OC(C)C(=O)C4=CNC5=CC=CC=C54)C=C3)C2=O)C=C1

Evidence for compound's anti-virulence activity:

Burkholderia
Related VF: Bsa T3SS
Target: BsaS
Drug effect: Inhibits BsaS ATPase activity.
Max phase: Preclinical (in vitro)
Publication:
Swietnicki W, et al., 2011. Identification of small-molecule inhibitors of Yersinia pestis Type III secretion system YscN ATPase. PLoS One 6(5):e19716.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: YscN
Drug effect: Blocks translocation of Yop effectors.
Max phase: Preclinical (in vivo)
Publication:
Swietnicki W, et al., 2011. Identification of small-molecule inhibitors of Yersinia pestis Type III secretion system YscN ATPase. PLoS One 6(5):e19716.