Drug details:
Molecular formula: C₁₉H₁₅Cl₂NO₅

Standard name: (4E)-2-(3,4-dichlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-oxazol-5-one

Curated SMILES: COC1=CC(/C=C2/N=C(C3=CC(Cl)=C(Cl)C=C3)OC2=O)=CC(OC)=C1OC

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Hu X, et al., 2013. Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches. Bioorg Med Chem Lett 23(4):1056-62.