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2,8-bis(5-methyl-2-furyl)pyrido[3,2-g]quinoline-4,6-dicarboxylic acid

Drug details:
Molecular formula: C24H16N2O6

Classification: Quinoline carboxylic acids; Quinolines and derivatives; Organoheterocyclic compounds; Organic compounds;
Synonym:  2,8-bis(5-methylfuran-2-yl)pyrido[3,2-g]quinoline-4,6-dicarboxylic acid

Chemical structure:
Depiction based on curated SMILES O OH O O H 3 C N N CH 3 OH O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Protein tyrosine phatase YopH inhibitor.
Max phase: Preclinical (in vitro)
Publication:
Eriksson J, et al., 2012. Small molecule screening for inhibitors of the YopH phosphatase of Yersinia pseudotuberculosis. Adv Exp Med Biol 954:357-63.








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