Drug details:
Molecular formula: C₃₄H₂₂N₄O₈S₂

Standard name: 2,6-bis[4-(4-aminophenyl)sulfonylphenyl]pyrrolo[3,4-f]isoindole-1,3,5,7-tetrone

Curated SMILES: NC1=CC=C(S(=O)(=O)C2=CC=C(N3C(=O)C4=CC5=C(C=C4C3=O)C(=O)N(C3=CC=C(S(=O)(=O)C4=CC=C(N)C=C4)C=C3)C5=O)C=C2)C=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Eriksson J, et al., 2012. Small molecule screening for inhibitors of the YopH phosphatase of Yersinia pseudotuberculosis. Adv Exp Med Biol 954:357-63.