Drug details:
Molecular formula: C₁₀H₁₄O₂

Standard name: tricyclo[3.3.1.03,7]nonane-3-carboxylic acid

Synonyms:

Octahydro-2,5-methanopentalene-3a-carboxylic acid 3-Noradamantane carboxylic acid 2,5-Methanopentalene-3a(1H)-carboxylic acid, hexahydro- tricyclo[3.3.1.03,7]nonane-3-carboxylic acid hexahydro-2,5-methanopentalene-3a(1h)-carboxylic acid hexahydro-2,5-methanopentalene-3a[1H]-carboxylic acid 3-NoradamantanecarboxylicAcid 3-Carboxynoradamantane 3-noradamantanecarboxylate (NAC) ......

Curated SMILES: C1C2CC3CC1CC3(C2)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.