Drug details:
Molecular formula: C₂₀H₁₀I₂O₅

Standard name: 2-(3-hydroxy-2,7-diiodo-6-oxoxanthen-9-yl)benzoic acid

Curated SMILES: C1=CC=C(C(=C1)C2=C3C=C(C(=O)C=C3OC4=CC(=C(C=C42)I)O)I)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.