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Gallocyanine

Drug details:
Molecular formula: C15H13ClN2O5

Classification: Phenoxazines; Benzoxazines; Organoheterocyclic compounds; Organic compounds;
Synonyms:  Gallocyanin
1-Carboxy-7-(dimethylamino)-3,4-dihydroxyphenoxazin-5-ium chloride
Solid Violet
Gallocyanine BS
Gallocyanine DH
Fast Violet
Anthracene Blue SWGG
Alizarine Navy Blue AT
Brilliant Chrome Blue P
......

Chemical structure:
Depiction based on curated SMILES HO O OH O HO CH 3 N CH 3 N

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.








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