Drug details:
Molecular formula: C₂₄H₄₀O₃

Standard name: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

Synonyms:

Lithocolic acid Lithocholate 3alpha-Hydroxy-5beta-cholan-24-oic acid 3alpha-Hydroxy-5beta-cholanic acid 3-Hydroxycholan-24-oic acid 3alpha-Hydroxycholanic acid 3-alpha-Hydroxycholanic acid 5beta-Cholanic acid-3alpha-ol 3|A-Hydroxy-5|A-cholanic acid ......

Curated SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.