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Mordant Orange 1

Drug details:
Molecular formula: C13H9N3O5

Classification: Azobenzenes; Organoheterocyclic compounds; Organic compounds;
Synonyms:  Alizarine Yellow R
Alizarin Yellow R
Alizarine Yellow RW
C.I. Mordant Orange 1
Pnbas
Magracrom Orange
5-(p-Nitrophenylazo)salicylic acid
Chrome Orange N
Chrome Orange R
......

Chemical structure:
Depiction based on curated SMILES _ O O + N OH O HO N N

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.








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