Drug details:
Molecular formula: C₂₃H₂₇N₂O₆

Standard name: CHEMBL227379

Curated SMILES: CC1(C)CC(NC(=O)/C=C/C2=CC=C(C3=CC(C(=O)O)=C(O)C=C3)O2)CC(C)(C)N1[O-]

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Leone M, et al., 2010. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des 76(1):10-6.