Drug details:
Molecular formula: C₂₆H₁₉F₂N₃O₆S

Standard name: 5-[5-[(E)-3-[[3-[[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]amino]-3-oxopropyl]amino]-3-oxoprop-1-enyl]furan-2-yl]-2-hydroxybenzoic acid

Curated SMILES: O=C(/C=C/C1=CC=C(C2=CC(C(=O)O)=C(O)C=C2)O1)NCCC(=O)NC1=NC(C2=CC=C(F)C(F)=C2)=CS1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Leone M, et al., 2010. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des 76(1):10-6.