Drug details:
Molecular formula: C₂₅H₂₀N₄O₇S

Standard name: 2-hydroxy-5-[5-[(E)-3-[[3-[[3-(4-hydroxyphenyl)-1,2,4-thiadiazol-5-yl]amino]-3-oxopropyl]amino]-3-oxoprop-1-enyl]furan-2-yl]benzoic acid

Curated SMILES: C1=CC(=CC=C1C2=NSC(=N2)NC(=O)CCNC(=O)/C=C/C3=CC=C(O3)C4=CC(=C(C=C4)O)C(=O)O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Leone M, et al., 2010. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des 76(1):10-6.